- Autoimmune disease is on the increase.
Virtually every autoimmune disease is on the increase in society.
This refers to a spectrum of diseases including inflammatory arthritis, thyroid, bowel or even neurological conditions such as multiple sclerosis and peripheral neuropathy.
The combination of fructose and polyunsaturated oils creates a susceptibility in organ systems and immune-suppression may make us more inclined to develop conditions of autoimmune disease.
This may be related to the same process that occurs in the theoretical development of Cancer that I have described in the Cancer section and is repeated below.
There is nothing to lose from reducing the sugar and processed food intake in the diet for a few months and seeing what happens.
Theoretical Cancer Model and Autoimmune Disease
There are three phases to the development of a cancer with relationship to my theory. The same applies to most other disease and possibly Autoimmune Diseases.
The first is to create low grade inflammation. The cell in an organ then undergoes what is called metaplasia, just like you develop a callus on the bottom of your foot when running barefoot over time. That chronic irritation creates a change in cells. If irritation continues over a longer period of time then those cells can start developing abnormalities and some of them may in fact turn into cancer cells (dysplasia and in to anaplasia).
Those cells then have the ability to divide and if they are in the right inflamed and vascular environment they can potentially grow.
The third aspect is that the body has natural clearing mechanisms within it for taking away abnormal cells and material. There are white cells that are responsible for this activity. Under a Fructose high environment, they appear to have poorer function and motility. This means you have a relatively immunosuppressed system for clearing up any abnormal cells that are developing in the body.
The combination of these three entities with increasing abnormal cells, growing in an inflamed environment and not being able to be cleared away falls well within a model for creating a cancer.
I clearly feel this requires further research and may be that is the next step we are heading to.
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High Levels of Both n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids in Cord Serum Phospholipids Predict Allergy Development by Malin Barman et al in http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067920
Dunder T, Kuikka L, Turtinen J, Räsänen L, Uhari M (2001) Diet, serum fatty acids, and atopic diseases in childhood. Allergy 56: 425–428. doi: 10.1034/j.1398-9995.2001.056005425.x.
Sausenthaler S, Kompauer I, Borte M, Herbarth O, Schaaf B, et al. (2006) Margarine and butter consumption, eczema and allergic sensitization in children. The LISA birth cohort study. Pediatr Allergy Immunol 17: 85–93. doi: 10.1111/j.1399-3038.2005.00366.x.